During the collision between the India and Eurasia plates, the movements in the interior of the blocks and relative moving among these blocks occurred in the Qinghai Xizang(Tibet)Plateau. The former is represented by the south north strike normal faults within the Lhasa Block and the latter by some right lateral strike slip faults along the northern margin of the Lhasa Block. The Ziguicuo active fault is typical one of strike slip faults, whose right lateral activities in the Quaternary cut rivers, alluvial fans and abandoned banks. The horizontal offsets of the fault range from 10 m to 375 m, and the vertical one not conspicuous. The Ziguicuo fault, being an important part of the Karakorum Jiali fault zone, connects the Pengqu Shenzha normal fault and the Karakorum Jiali fault. The activity of the Ziguicuo fault implies that the Lhasa Block might be east west extending and the Qiangtang Block might be eastward moving.