The Lunnan Lower Uplift, a sub unit of the North Tarim Rise in the Tarim Basin, was characterized with multiple productive reservoirs, various pool types and multi phases of hydrocarbon generation, migration and filling to the pools. Superimposed vertically and located one next to another in lateral, the pools of various types in the Lunnan Lower Uplift constituted a typical multiple oil-gas accumulation play. The petroleum geological theory of multiple oil-gas accumulation play was inducted out from the petroleum exploration and development in the Bohai Sea Basin. It was successfully applied in the petroleum exploration in the rift petroliferous basins in East and South China. The Lunnan multiple oil-gas accumulation play indicated that this theory could also bright prospect of application and development in the compressive petroliferous basins in West China.