The Yili Basin is an important uranium-productive basin in Northwest China, although its metallogenic fluid was studied systematic by predecessor, the problem about its component and source still exist, especially about the internal relation between metallogenic fluid and alteration characteristics and uranium mineralization. In this paper, the methods of polarizing microscope, scanning electron microscope, electronic probe was utilized to analysis alteration characteristics of sandstone in the ore-bearing layer systematically. At the same time, the fluid inclusions in ore-bearing sandstone，the stable isotope about altered mineral which was formed by interaction between fluid and wall rock and the tectonic evolution about Yili basin were show that the fluid inclusions in ore-bearing sandstone include gas-hydrocarbon inclusions,liquid-hydrocarbon inclusions and brine-inclusions. The type of alteration which related to sandstone-type uranium deposit mainly include clayzation, carbonation, silication and metal mineralization and the clayzation was first and foremost, the δDV-SMOW and δ18OV-SMOW of kaolinite is varies from -93‰ ～ -48.3‰ , 11.8‰ ～ 13.7‰ respectively and the δ 18OV-SMOW of relevant fluid varies from -10.3‰～-5.1‰; the δ13CV-PDB, δ18OV-PDB and δ18OV-SMOW of the carbonate cement is range between -18.2‰ and -7.2‰, -14.5‰ and -5.8‰, 15.9‰ and 24.9‰; the δ34SV-CDT of pyrite is range from -32.21‰ to 1.2‰ respectively. The above characteristics reveal that the metallogenic fluid of sandstone-type uranium deposit in the southern margin area of Yili basin is mixed fluid which consists of surface-water stemming from meteoric waters and organic acid originating from coal measure strata and its concomitant reducing gas（coal-formed gas）. In addition, the uranium ore and altered mineral was the result from reciprocity of organic-inorganic fluid and fluid-rock and microorganism was exist in the mineralization process.
Ding Bo Liu Hongxu Li Ping Wang Maomao Jiang Hong Zhang Xiao Pan Chengyu Xiu Xiaoqian. The organic-inorganic fluid coupling uranium mineralization in the southern margin of Yili Basin[J]. Chinese Journal of Geology, 2017, 52(3): 871-894.