Karakum Basin, which is located in the south of Turan platform, NW trending, is one of the most important petroliferous basins in central Asia. The tectonic attributes of basin in Late Permian-Triassic has always been around a lot of controversy. According to the drilling, geophysics and outcrop data, we think that the Karakum Basin is a sedimentary basin which has a basement with accretionary complexes. It has nature of back-arc rift in Late Permian-Triassic. The evolution of Pre-Jurassic in Karakum Basin can be divided into four stages:1)Paleotethys oceanic crust began to subduction before Carboniferous; 2)Silk Road Arc formed in Carboniferous-Early Permian; 3)Karakum Basin is located in the back-arc extensional position when Mashhad-North Pamir Arc formed in Late Permian-Triassic; 4)Karakum Basin became a peripheral foreland basin in short week stage when Iran blocks collided with Eurasia in the end of Late Triassic. The depocenter of basin is North Amu-Darya, Murgab and Kopet Dag foredeep. The depositional environment is conventional facies, and some areas received transgression and became marine in Triassic. Rock types are mainly siliciclastic rocks, volcanic rocks and a small amount of limestone.