The Zhalage gold deposit is located in the Tengchong-Bange magmatic arc at the northern margin of the Gangdese-Nianqingtanggula terrane, in the eastern part of the Bangong-Nujiang suture. Its occurrence is controlled by a suite of abyssal flysch, brittle-ductile shear zone, and plutonic magma activity. The fluid inclusions are mainly of single-phase or A-type double-phase salt-water systems, and subordinately B-type double-phase or CO2-enriched double-and three-phase salt-water systems. The ore-forming fluid belongs to an epithermal to mesothermal(120 ℃～340 ℃)H2O-NaCl-CO2 system with low to moderate salinity(6.4%～14%). The hydrogen and oxygen isotopes and the liquid phase composition of the fluid inclusions which are enriched in K+, Na+, Ca2+, Mg2+, Cl-, SO2-4 indicate that the ore-forming fluids were dominantly deep-circulating hot brine water that is chronically stored within the sedimentary rocks. The gold deposit was formed through leaching by hot brine water under hypabyssal epithermal-mesothermal conditions. The Zhalage gold deposit resembles the Muruntau gold deposit in terms of ore-forming geological background, and the characteristics of ore geology and ore-forming fluid. It is likely that a breakthrough can be achieved if more invests can be put for the exploration of the "sandin slate" gold-copper polymetallic ore in the region.