Based on the terrestrial heat flow and the two-dimensional steady-state heat conduction equation,a 2-D geological-geophysical model along the Fengjie-Guanyindang geotraverse in mid-upper Yangtze area was constructed. The profile crosses Chuandongbei regions,Zigui Basin,Huangling Dome and Jianghan Basin. The temperature field was calculated under the constraints of heat production rate,thermal conductivity along the profile. The simulation results show that mantle heat flow along the profile increases gradually from west to east ranging from 24.8 to 35.5 mW/m2. The temperatures at Moho vary from 380 ℃ to 450 ℃. From west to east,thickness of the thermal lithosphere increases slightly then decreases gradually,ranging from 115 km to 171 km. The extension in Meso-Cenozoic raised the mantle heat flow in Jianghan Basin. While the compressional tectonic background and denudation made mantle heat flow in Chuandongbei regions lower with thick thermal lithosphere.